Voltammetric determination of carbidopa using a modified multiwall carbon nanotube paste electrode

Esta vez la voltamperometría se utiliza para determinar carbidopa, con la particularidad de que se usa un electrodo de pasta de nanotubos de carbono modificado. El estudio se lleva a cabo con voltamperometría cíclica y con voltamperometría de onda cuadrada.

A modified carbon nanotubes paste electrode (MCNTPE) was used for the sensitive voltammetric detn. of carbidopa (CD) in buffer soln. using cyclic voltammetry (CV), square wave voltammetry (SWV) and chronoamperometry (CHA).  The diffusion coeff. (D = 2.62 × 10-5 cm2 s-1) and the kinetic parameter such as the electron transfer coeff. (α = 0.37) of CD oxidn. at the surface of MCNTPE was detd. using electrochem. approaches.  It has been found that under an optimum condition (pH 9.0), the oxidn. of CD at the surface of the modified electrode occurs at a potential about 100 mV less pos. than that of an unmodified carbon nanotubes paste electrode.  SWV of CD at the modified electrode exhibited linear dynamic range with a detection limit (3σ) of 0.4μM.  Finally, this modified electrode was also examd. for the detn. of CD in urine samples.

Mohadesi, Alireza

International Journal of Electrochemical Science (2012), 7(3), 2430-2439