Carbon paste electrode prepared from chemically modified multiwall carbon nanotubes for the voltammetric determination of isoprenaline in pharmaceutical and urine samples

La voltamperometría con electrodo de pasta de carbón con nanotubos de carbono de multiparedes modificados químicamente (con N-(3,4-dihydroxyphenethyl)-3,5-dinitrobenzamide) ha vuelto a ser estudiada para el análisis de un compuesto en cantidades traza. En este artículo se determina isoprenalina en muestras de orina y farmacéuticas

A carbon paste electrode with added multiwall carbon nanotubes chem. modified with N-(3,4-dihydroxyphenethyl)-3,5-dinitrobenzamide was used as the electrochem. sensor for the detn. of trace amts. of isoprenaline.  The modified electrode showed good electrocatalytic activity for the anodic oxidn. of isoprenaline, which was due to a substantial decrease in the anodic overpotential.  Under the optimum conditions, measurements using square wave voltammetry had a linear range in the range of 0.3 to 125.0 μmol/L of isoprenaline and a detection limit of 0.1 μmol/L.  The diffusion coeff. and kinetic parameters were detd. using electrochem. methods.  The relative std. deviation for seven successive assays of 1.0 and 20.0 μmol/L isoprenaline were 1.9% and 2.4%, resp.  This electrochem. sensor was successfully applied for the detn. of isoprenaline in human urine and injection soln. samples.

• Ensafi, Ali A.; Bahrami, Hajar; Karimi-maleh, Hassan; Mallakpour, Shadpour
• Cuihua Xuebao (2012), 33(12), 1919-1926