Simultaneous differential pulse voltammetric determination of dopamine and uric acid with polycalconcarboxylic acid modified glassy carbon electrode

En este artículo la voltamperometría de pulso diferencial tiene la particularidad de ser utilizada con un electrodo vítreo de carbono modificado con ácido policarconcarboxílico. Los resultados obtenidos son buenos para la determinación simultánea de ácido úrico y dopamina.

• The modified electrode (PCCA/GCE) was prepd. by electrochem. polymn. of calconcarboxylic acid (CCA) on the surface of glassy carbon electrode (GCE).  The electrochem. property of the PCCA/GCE was studied by cyclic voltammetry and AC impedance method.  It was found that in a PBS of pH 6.0, the oxidn. peaks of dopamine (DA) and uric acid (UA) were completely sepd., and the p.d. of the oxidn. peaks attained to a value of 0.14 V.  Based on these findings, a selective method for simultaneous detn. of DA and UA by differential pulse voltammetry was proposed.  Linear relationships between values of oxidn. peak current and concn. of DA and UA were obtained in the ranges of 5.0-43.8 μmol·L^-1 and 5.0-50.0 μmol·L^-1, with their detection limits of 0.2 μmol·L^-1 and 0.5 μmol·L^-1, resp.  The proposed method has been used in simultaneous detn. of DA and UA in DA injections, giving values of RSD's (n = 5) of 2.43% for DA and 2.35% for UA.
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• Huang, Wen-hua; Hou, Bao-qin; Zhang, Lei
• Lihua Jianyan, Huaxue Fence (2012), 48(6), 638-642.